A selective and mild glycosylation method of natural phenolic alcohols

• Mária Mastihubová and
• Monika Poláková

Beilstein J. Org. Chem. 2016, 12, 524–530, doi:10.3762/bjoc.12.51

• to the stereoselective glycoside synthesis. The final products were obtained by conventional Zemplén deacetylation. Keywords: diastereoselectivity; p-hydroxyphenylalkyl glycosides; mild promoters; natural products; 1,2-trans-glycosylation; Introduction Arylalkyl (substituted benzyl, phenethyl and

• glycosides 1–3, 31a,b and 32–37 were isolated in high yields (Figure 3). Conclusion The glycosylation methods studied in this work represent a simple and convenient approach to bioactive natural p-hydroxyphenylalkyl glycosides and their analogues. The mild reaction conditions with exclusive stereoselectivity

• the synthesis of p-hydroxyphenylalkyl glycosides. Synthesis of 21a–c to 30 under various conditions. Supporting Information Supporting Information File 44: Experimental procedures and analytical data. Acknowledgements This work was supported by the Slovak Research and Development Agency under the